Cardiovascular system

 

Cardiac form, function. pathophysiology and management.

 

Introduction

The heart is a hollow organ divided into four chambers. The upper chambers are termed atria and the lower chambers ventricles. Blood from the venous circulation enters the atria where it is collected before passing through the atrioventricular valves into the ventricles. Ventricular contraction pumps blood out through the semi-lunar valves  into the arterial system to perfuse the lungs and body. The heart is therefore a blood pump. If for any reason the pumping action of the heart stops death will occur within minutes. This is because the tissues of the body are dependent on the circulation of the blood for their supplies of oxygen and nutrients.

 

The four chambers are the right and left atria and the right and left ventricles. Between the right atrium and ventricle is the tricuspid valve. The mitral or bicuspid valve divides the left atrium and ventricle. Between the ventricles and main arteries are the pulmonary arterial and aortic semi-lunar valves, (fig 1)

 

The three layers

The energy for the pumping action is generated by the heart muscle, this unique cardiac muscle is striped or striated  in nature and termed the myocardium. As the myocardium must contract approximately 72 times per minute it uses a lot of nutrients and oxygen. As with all other tissues these are supplied in the circulating blood. The first two arteries to leave the aorta are the right and left coronary arteries which perfuse the myocardium. Disease of these arteries is termed coronary artery disease and is a common cause of death in the Western world.

 

The inner layer of the heart is composed of smooth squamous epithelium. This allows the smooth uninterrupted flow of blood through the heart. This inner lining also covers the heart valves. The importance of this epithelium is highlighted by the effect of it becoming infected, a condition termed endocarditis. Usually caused by a streptococcus, this condition causes inflammation followed by deposits of fibrin causing the build up of "vegetation", (1). If this material is dislodged it will enter the circulatory system as emboli which can lodge in the small arterial supply of any part of the body.

 

The other layer of the heart is itself made up of two layers and termed the pericardium. The inner layer is composed of serous membrane and the outer layer of tough fibrous tissue. This allows the heart to expand and contract during the normal cardiac cycle. The fibrous layer is protective and prevents the heart over expanding. If fluid or blood collects under the pericardium the pressure can embarrass the heart and may cause death. This condition is termed cardiac tamponade, (2). 

 

Blood flow through the heart

The heart is essentially two pumps. The left side pumps blood to the body and the right side to the lungs. Blood is pumped to the lungs purely to be oxygenated. The haemoglobin in red blood cells absorbs oxygen and transports it via the left side of the heart to all the tissues of the body.  Both sides of the heart contract together, simultaneously pumping blood to lungs and body, (fig 2).

 

As the atria contract the pressure of the blood they contain increases, this has the effect of opening the atrioventricular valves allowing the blood to pass through into the ventricles. As the ventricles begin to contract the pressure of the blood in them increases. This causes the atrioventricular valves to close and the semi-lunar valves to open. This prevents the regurgitation of blood from the ventricles back to the atria and directs blood into the arterial system. The valves are therefore passive structures which open and close in response to pressure changes in the blood. They are prevented from opening in the wrong direction by tendinous cords which are attached to papillary muscles which extend from the inner cardiac wall.

 

The principle of pressure changes within the heart opening and closing valves is applied in external cardiac massage. This compresses the heart between the thoracic vertebral column and the sternum. As the pressure in the heart increases blood will open the valves and be forced through. As valves only allow the blood to flow one way the circulation can only occur in a physiological direction. Cardiac massage will generate a cardiac output which may be detected as a central pulse. This will perfuse the vital organs of the body such as the lungs, brain, kidneys and the heart itself. This can be maintained until a normal cardiac rhythm is restored.

 

As both atrioventricular valves close they make a sound referred to as a "lub". The closure of the two semi-lunar valves makes a "dub". These are termed the first and second heart sounds, so the normal heart should make a lub dub, lub dub, lub dub. Additional sounds may be abnormal and may be  caused by disturbances in the smooth flow of blood. An abnormal heart sound referred to as a "whoosh" is often heard in septal defects where there is a communication between the right and left side of the heart, (a "hole in the heart"), (3). The resultant mixing of oxygenated and deoxygenated blood reduces the efficiency of the circulatory system. In this case some oxygenated blood is returned to the lungs and some deoxygenated blood is pumped into the systemic circulation. Such conditions are usually congenital and require surgical correction.

 

Systemic and pulmonary circulation

The left ventricle contracts and the blood is ejected  through the aortic semi-lunar valve into the aorta. As the aorta passed through the thorax and abdomen, arterial branches leave to carry blood to all parts of the body. The arteries eventually divide down into arterioles which in turn supply blood to the capillary systems in all tissues, (except the lungs). After giving up oxygen and nutrients to the tissues and collecting carbon dioxide and waste products the blood is returned into venules (fig 3).These pass the blood into larger veins and eventually join the vena cava.

 

The vena cava empties blood directly into the right atria. From here blood passes through the tricuspid atrioventricular valve into the right ventricle. This discharges blood via the pulmonary artery semi-lunar valve into the pulmonary artery. The right and left branch of this artery supply the two lungs with blood, perfusing the pulmonary capillaries. During circulation through the alveoli the blood gives up waste carbon dioxide and picks up oxygen. Returning blood from the lungs enters the left atria via the pulmonary veins. When the right atria contracts the blood passes through the mitral or bicuspid valve into the left ventricle to complete one cycle, (fig 4). 

 

The muscle mass of the left ventricle is greater than that of the right. This is because the pressure required to perfuse the body is greater than that needed to pump blood to the lungs. A typical pressure in the systemic circulation is 120/80 mmHg whereas in the pulmonary circulation it is 25/8 mmHg (4). The first pressure is taken when the heart is contracting and referred to as the systolic pressure. The second pressure is recorded when there is no active cardiac contraction in between beats. This reflects the elasticity of the arterial system and is termed the diastolic pressure.

 

The cardiac cycle

The heart contracts at a regular rate from about eight weeks after conception until the death of the individual. The rate varies with the age of the individual from about 140 at birth to around 110 at age two, 80 at age ten to around 70 in adults.

 

The internal conducting system

The cardiac cycle is controlled  by specialised conduction tissue in the heart. Inside the right atrium is an area termed the sino-atrial, (SA) node. This generates the initial impulse to stimulate the myocardium to contract. This impulse spreads to both atrium stimulating their contraction. The specialised conduction tissues are termed the internodal tracts because they are between the SA node and the atrioventricular (AV) node. The AV node collects the impulse from the atria and passes it on to the bundle of His (or atrioventricular bundle) in the cardiac septum. This divides into two forming the right and left bundle branch. Finally the impulse innovates the ventricular myocardial muscle via the Purkinje fibres. This internal conducting system allows the phases of a cardiac cycle to be co-ordinated, (fig 5), (5)

 

The PQRST

When the myocardium is stimulated there is an electrical change in the myocardial muscle associated with contraction. This electrical activity may be detected with electrodes on the surface of the body. This is the principle of the electrocardiogram. When this is done three characteristic electrical phases can be clearly noted.

 

Firstly there is a P wave. This is the electrical activity as detected on the surface of the body as a result of the contraction of the artial myocardium. Secondly there is the larger QRS complex caused by the contraction of the larger muscle mass of the ventricular myocardium. Thirdly there is a T wave. This is not associated with any muscular contraction but arises as the ventricular muscle returns to an electrically resting state. Finally there is then a short gap before the next atrial contraction. The normal cardiac cycle therefore has a PQRST in that order, (fig 6). In health the occurrence of these phases of the cycle is regular and the rate is between 60 and 100 per minute. If these three criteria are met the individual is in sinus rhythm, ie. the cardiac rhythm is controlled by the sino-atrial artial node, (table 1).

 

If the phases of the cardiac cycle occur regularly and in the correct order at a rate of less than 60 times per minute the rhythm is termed sinus bradycardia. This is normal in people who are physically fit, (fig. 7). If the rate is over 100 and the other two criteria are met it is a sinus tachycardia. A sinus tachycardia is of course normal during exercise, (fig. 8).

 

The terms P,Q,R,S and T do not stand for anything and have no intrinsic significance what so ever. They are arbitrary names given to specified phases.

 

 

Coronary arterial disease

 

The reason it is so vital for nurses to have a knowledge of normal and abnormal cardiac function is because coronary arterial disease is the main single cause of premature death and disability in the Western world. In the UK cardiovascular disease kills 350 000 people every year (6). These premature deaths are arguably almost all preventable. The site of pathology is the coronary arteries which perfuse the myocardium. The first two vessels which leave the aorta are the right and the left coronary arteries which sub-divide into other arteries which perfuse the capillaries of the myocardium. The myocardium is an active muscular tissue and therefore requires a constant supply of blood.

 

Fatty material is deposited into the wall of the coronary arteries in an irregular way. In general this has three effects. Firstly the deposited material reduce the lumen of the artery, therefore reducing the volume of blood than can travel through that section of artery. The effect of this is  the tissue that particular artery supplies  receives less blood than normal. This reduced blood supply is termed ischaemia. Secondly because the fatty material is laid down irregularly blood may start to clot on the uneven surface. This can build up and form a blood clot or thrombosis. This may completely occlude the lumen of the artery leading to the effected tissue being totally deprived off its blood supply. This is termed an infarction, the area of tissue cut off from it is blood supply is the area of infarct. Thirdly the wall of the artery may be weakened resulting in blood leaking from the artery, this is termed an aneurysm, (table 2).

 

The fatty material deposited into the wall of the arteries is referred to as atheroma, the arteries are described as atheromatous. The disease process is correctly termed atherosclerosis, (fig 9). The aetiology of atherosclerosis is the focus of much debate, but some of the commonly accepted factors are given in table 3. (7)

 

As health educators nurses can help people to change the risk factors in their life styles which contribute to the aetiology of CHD. This will reduce the risk of the development of the condition. Nursing support often needs to be an on-going process. Risk factors such as diabetes and hypertension are directly related to the degree of control of these chronic underlying conditions. If they are well controlled by diet, exercise and good medication compliance their pathogenic effect can be largely negated. The question as to whether atherosclerosis is a reversible process is currently under debate, however recent research seems to indicate that with life style changes it is, at least partly, reversible, (8).

 

List some lifestyle factors which you know of that may lead to atherosclerosis.

 

Diet high in polysaturated fat and sugar

Lack of water soluble fibre and vitamins caused by lack of fresh fruit and vegetables

Smoking

Lack of aerobic excecise, 20 - 30 minutes most days is recomended

Psychological stress

Obesity

 

 

While lifestyle factors are important in the development of atherosclerosis, they are not the only factors. Genetic factors certainly play a part in the aetiology. Coronary heart disease is also more common in children who have had low birth weights and some researchers have postulated that there is a link to organisms such as helicobacter and clostridia.

 

We have mentioned that  atheroma in the coronary vessels can lead to angina and infarction.

 

List some other conditions caused by arterial pathology which may affect other parts of the body.

 

Stroke and transient ischaemia attacks

Mesenteric ischaemia

Peripheral vascualar disease

Arterial leg ulcers

 

 

Angina

 

Angina pectoris or angina of effort is a pain of myocardial origin. Typically it is described as a tight or crushing chest pain often referred into the left arm. The severity of pain may vary from mild to very severe and there may be numbness or weakness in the arms. The patient often suffers extreme apprehension and fear of death. In angina of effort the atheromatous coronary arteries can supply enough blood to the myocardium for normal function at rest. However with exercise the work load, and hence oxygen requirement of the myocardium increase. This results in myocardial ischaemia which causes the pain. The situation is analogous to cramp in a leg muscle.

 

The pain causes the individual to stop the exercise and   usually passes off within a few minutes. This is because at rest the oxygen consumption of the myocardium is reduced and the reduced perfusion once again becomes adequate. The action of drugs such as Glycerine Trinitrate is to dilate the coronary arteries and so allow more blood to flow into the myocardium to prevent or treat the hypoperfusion.

 

Patients should be advised to avoid sudden strenuous exercise, especially after meals and in cold weather.  Heavy meals should be avoided. If overweight advice should be given on weight reduction, this will reduce the tissue mass the heart is required to perfuse with blood therefore reduce myocardial work load and oxygen requirement. It is particularly important for angina sufferers not to smoke. Smoking increases the amount of carbon monoxide in the blood which reduces it`s oxygen carrying capacity. Smoking is also likely to increase the amount of atheroma. Nicotine will have a vaso-constricting effect on the coronary arteries and also make an infarct more likely to occur. Anaemia should be recognised and treated. This will increase the volume of oxygen which can be transported by a given volume of blood. Emotion and excitement can also precipitate an attack.

 

If  the lumen of the coronary artery is narrowed or the coronary arteries spasm for any reason then there will be a reduction in the amount of blood supply to the myocardium. This will result in angina pectoris, the pain caused by myocardial ischaemia.

 

Describe what is meant by the term angina.

 

Angina describes the pain caused by myocardial ischaemia.

 

Angina is caused by reduced blood supply to the heart muscle or more precisely by an imbalance between myocardial oxygen demand and the amount of oxygen the myocardium is receiving. 

 

What are the clinical features of this angina?

 

The pain is typically `heavy` and `constricting`, it occures as a central chest pain which may radiate into the left arm. It may also radiate through to the back, down to the epitgastric region, into the right are and into the lower jaw. The pain may be accompanied by anxiety and sweating

 

 

Myocardial infarction

 

The pain of myocardial infarction (MI) is typically described as severe, crushing, tight and heavy. As in angina the pain is usually felt in the chest and often radiates into the left arm. It may also be referred down to the epigastrium, through to the back, up to the jaw and even sometimes into the right arm. Pain is of sudden onset and may come on during exercise, rest or sleep. The pain does not pass off at rest and is not relieved by nitrates.

 

The pain is caused by an area of myocardium which is suddenly deprived of its blood supply because of the formation of a thrombosis in the coronary arterial blood supply, (fig 10). Streptokinase given shortly after an MI can dissolve the clot, restoring the blood supply before the infarcted myocardium dies. Such thrombolytic agents are now commonly used throughout the UK. Thrombolytics should be given as soon as possible after the onset of symptoms to minimise myocardial cell death. This comparatively new treatment offers the possibility of a coronary thrombosis which does not result in a myocardial infarction.

 

As the pain is severe diamorphine is usually given intravenously in hospital, this will also have an anxiolytic effect. An antiemetic is given to prevent the nausea and vomiting associated with opiate use. Psychological support is  vital. If the nurse reduces the level of patient anxiety the levels of circulating adrenalin will consequently be reduced. As one effect of adrenalin is to increase the excitability of the myocardium, allaying anxiety may reduce the probability of ventricular fibrillation. As emergency intervention may be needed in initial management an intravenous cannula should be inserted and kept patent. Much of the further nursing management of an acute MI is based on the early recognition and prevention of complications. Throughout all management and patient education the individual and his or her significant others should be closely involved.

 

 

Complications of Myocardial infarction

 

Arrhythmia

An infarcted area of myocardium will rapidly start to die, as will any tissue deprived of a blood supply. As the cells become increasingly embarrassed they lose the ability to control the electrical potential difference across their cell membranes. Such areas of infarcted tissue are therefore in an electrically unstable condition. If they start to transmit these abnormal electrical signals to other healthy areas of myocardium, cardiac contraction will become abnormal. The infarcted area therefore becomes a site or focus for electrical activity. As the normal focus for electrical activity is the SA node the new area is out of place, it is therefore referred to as an ectopic focus.

 

When the myocardial muscle attempts to respond to an ectopic focus the normal rhythm is disturbed and becomes an arrhythmia. The most common life threatening arrhythmia is a rapid uncoordinated contraction of the myocardium termed ventricular fibrillation, (VF). In this arrhythmia there is no cardiac output at all so the blood pressure is zero. This is termed a cardiac arrest. The patient is collapsed with no central pulse If uncorrected death will occur in about three minutes as the brain becomes increasingly hypoxic. The ECG will reveal a characteristic pattern quite unlike sinus rhythm, (fig. 11). Cardiopulmonary resuscitation will maintain some circulation until a definite diagnosis is made and defibrillation carried out. If VF occurs it is usually in the first few hours after the infarct. It may however occur within a few minutes or even seconds. All patients with an MI should therefore be closely observed on a cardiac monitor as soon as possible, usually for 24 hours. Full resuscitation facilities should always be immediately available.

 

Heart block

If any part of the internal conducting system is infarcted it will no longer be able to transmit internal impulses. There are basically three degrees of severity of heart block. In the most severs case it may mean that the ventricles are not innovated to contract and a ventricular standstill result. If this occurs the patient will usually require a temporary or permanent pace-maker to artificially stimulate ventricular contraction, (9).

 

Cardiac rupture

Sudden exertion in the week after an infarction will increase the pressure of the blood inside the heart. This may result in a breach of the weakened cardiac wall causing fatal haemorrhage. With time the infarcted area will heal as fibrous tissue forms in the infarcted area, this will seal the heart wall allowing gradually increasing exercise. From this it is clear that patients after myocardial infarction should not be subject to strenuous exercise in initial management.

 

Heart failure

If the pumping activity of the heart is compromised cardiac failure may develop. This usually first effects the left ventricle leading to left ventricular failure, (LVF). Heart failure may be acute or chronic and usually is a complication of myocardial infarction or atrioventricular valve disease, (10).

 

If an area of myocardium is infarcted then the pumping efficiency of the heart will be reduced. This may result in some blood being left in the left ventricle after contraction. When the atria empties into the ventricle some of the blood will not be able to enter due to the presence of blood in the ventricle from the previous contraction. This means some blood will be left in the left atria. This backlog of blood in the atrial will restrict the emptying of the pulmonary veins increasing the pressure of the blood in them. This will in turn dam back to the pulmonary capillaries, increasing the pressure in their venous ends. This increased hydrostatic (fluid) pressure, in the capillaries will reduce the reabsorption of tissue fluid leaving free fluid in the lung tissues. This is pulmonary oedema.

 

Typically such patients suffer difficulty in breathing (dyspnea) when lying down, (orthopnea) and have to sleep in a sitting position. This is because the fluid covers the lung fields when the patient is recumbent, preventing gaseous exchange. Acute LVF is life threatening and often diagnostic pink frothy sputum is expectorated. The aim of management is to improve cardiac function  and prevent the problems of the fluid backlog. Fluid input and output should be closely monitored and no additional salt should be given in the diet. Patients should be nursed sitting up or leaning forward. Diuretics will usually be given to reduce the fluid overload that develops. In cyanosis or respiratory distress oxygen supplementation may be given. Diet should be light and easily digestible as large meals will increase the gastrointestinal blood supply demand.

 

The term congestive cardiac failure usually refers to right ventricular failure (RVF). The backlog of blood will lead to congestion effecting all of the body, (except the lungs). Systemic oedema in the tissue spaces and will be influenced by gravity and collect in the feet and ankles, or sacrum if the patient is in bed. The presence of oedema is a risk factor for the development of pressure sores. The oedema increases the distance from the blood capillaries to the tissue cells, this may adversely effect cell nutrition and oxygenation.  Regular re-assessment and positional change are therefore particularly important. The backlog of blood in the systemic veins may be noted as distension in neck veins. This raised jugular venous pressure is indicative of raised venous pressure.

 

Reduction of physical activity is usually indicated as it reduces the demands placed on the heart. Bed rest is sometimes prescribed for a few days to facilitate this. The risk of deep venous thrombosis should be minimised by regular active and passive leg exercises, and the possible use of elastic support stockings and low dose subcutaneous heparin. (11). Alcohol should be avoided as it reduces the strength of cardiac contraction.

 

RVF may develop following left ventricular failure or more acutely as a consequence of right ventricular dysfunction. As the congestion progresses all organs of the body may become congested with blood leading to multiple organ failure, eg. so called cardiac cirrhosis.

 

So in congestive cardiac failure the heart if unable to maintain sufficient cardiac output in the presence of normal or even increased venous return.  This results in a backlog of blood in the venous system which can cause congestion in all organs of the body. The incidence of this condition is approximately ten per thousand in those over the age of sixty five and approximately fifty percent of individuals with severe failure die within two years.

 

List some conditions of the heart or circulatory system which may give rise to congestive cardiac failure. 

 

Myocardial infarction

Cardiomyopathy

Vavular disease

 

 

The initial clinical picture in congestive cardiac failure depends on the side of the heart first affected. In right ventricular failure the backlog of blood starts in the right ventricle and dams back into the right atria and from there into the into the vena cava the rest of the systemic veins. This may mean that there is systemic venous congestion.

 

List any effects you can think of chronic venous congestion.

 

Increased pulmonary venous pressure may lead to pulmonary oedema

Systemic venous congestion may lead to congestion anf failure of almost any organ, eg liver failure.

It may also lead to oedema of the legs

 

 

The second type of heart failure is left heart failure, or left ventricular failure.  Here, as the left ventricle is not working properly the blood dams back into the left atria then into the pulmonary arteries and into the lungs causing oedema in the lungs.

 

What clinical feature may be caused by pulmonary oedema?

 

Difficulty in breathing, especially when the patient to breath lying doen, (orthopnoea). This is due to an accumulation of fluid in the lungs.

 

 

Which group of drugs may be given to reduce the volumes of fluid in the body?

 

Diuretics, eg. frusamide

 

 

 

What other drugs may be used in congestive cardiac failure?

 

Diuretics with possible potassium suplement

Digoxin

ACE (Angiotensin converting enzyme) inhibitors

Nitrates

Cardiac glycosides

 

Shock

The heart is a pump and derives the energy to pump from the myocardial muscle. If a section of this muscle dies it will not regenerate as muscle cells do not undergo mitosis. The infarcted area will fibrose in time but will not be contractile and will not contribute to cardiac pumping activity. The result will be a non moving  area in the myocardium, ie. it will be dyskinetic. If the myocardium is no longer able to generate a pumping pressure sufficient to perfuse the tissues of the body the state of hypotension is termed cardiogenic shock. The term shock means a state of acute hypotension.

 

This reduced blood pressure will reduce the perfusion of the myocardium itself which may lead to further reduced myocardial function. Hypoperfusion of the brain will mean the patient feels dizzy when they sit up and they may faint. It is important to allow patients to stabilise in a sitting position before standing upright. Close support and observation should be given. Inadequate perfusion of the kidneys may lead to oliguria or anuria leading to damage of the nephrons termed acute tubular necrosis. If the reduced perfusion persists acute renal failure will ensue. In order to closely monitor renal function the patient will be catheterised with hourly urine volumes recorded. All fluid input and output will be recorded and a balance calculated. 

 

Other features which may indicate the onset of cardiogenic shock include cool moist skin and peripheral cyanosis, resulting from poor superficial perfusion. In hypotension there is peripheral vasoconstriction to conserve blood to supply the vital organs. Reduced perfusion of the brain may cause restlessness, anxiety, apathy or lessening of responsiveness.

 

In cases of coronary heart disease there may a thrombosis formed in the coronary artery which would result in a area of myocardium infarction.

 

Describe in your own words what is meant by the term myocardium infarction.

 

Myocardail infactrion describes an area of infarct in the myocardium. This is an area deprived of a blood supply. When the blood supply is cut off the area of muscle deprived starts to die and will eventually necrose.

 

 

Myocardial Infarction typically has an acute presentation and the person complains of severe pain.

 

Describe the nature and distribution of the pain which you might expect to see in the case of acute myocardial infarction.   

 

The pain is typically very severe and `heavy` and `constricting`, it occures as a central chest pain which may radiate into the left arm. It may also radiate through to the back, down to the epitgastric region, into the right are and into the lower jaw. The pain may be accompanied by anxiety and sweating.

 

Unlike angina pain in myocardial infarction does not pass off with rest

 

 

A myocardial infarction is usually caused by a coronary arterial thrombosis.

 

What immediate medical treatment may be given to reduce the amount of damage to the myocardium following a coronary thrombosis?

 

The main line of treatment is to give an aspirin at once and to administer thrombolytic therapy as soon as possible.

 

 

After a myocardial infarction there are several complications which may occur. One of these is due to the area of infarcted myocardium starting to die, it may act as an ectopic electrical focus and generate ectopic electrical impulses at a rapid rate.

 

What may these ectopic electrical impulses cause in terms of cardiac arrhythmias?

 

Ventricular ectopics

Ventricular tachycardia

Ventricular fibrallation

Atrial flutter

Atrial fibrillation

 

 

In addition to cardiac arrhythmia, because there is an area of dead muscle in the myocardium the heart may not be able to pump as efficiently as it could prior to the infarction.

 

What condition may be caused by reduced pumping capacity of the myocardium?

 

Cardiogenic shock

 

 

Relationship of pathophysiology to nursing observations

 

Temperature

Pyrexia occurs as a response to infection or tissue damage. After myocardial damage there is often a low grade pyrexia. This is due to the damaged tissue releasing pyrogens which influence the hypothalamus and is not indicative of infection. However viral or bacterial infection in the heart can lead to a pyrexia of infectious origin. Inflammatory conditions may have the same effect. If an individual is immobile pyrexia may indicate the onset of hypostatic pneumonia or possibly deep venous thrombosis. Reduced peripheral temperatures may indicate reduced tissue perfusion.

 

Pulse

The rate rhythm and general quality of the pulse should be regularly assessed. A weak or absent peripheral pulse may indicate poor cardiac output. A fast thready pulse is usually caused by shock. Sometimes an abnormal cardiac rhythm may be felt in the pulse such as the coupling of the beats in a so called bigeminal pulse. Missed beats may indicate ventricular ectopic beats and an irregular pulse may be caused by atrial fibrillation, (fig. 12). In routine situations the radial pulse should be used, however in emergency situations a central pulse such as the carotid or femoral should be palpated. If the systolic blood pressure is below about 75 mmHg there will be no radial pulse palpable, however a systolic of 50 mmHg will generate a palpable central pulse. The rate of the pulse will indicate the presence of a tachycardia or bradycardia.

 

Blood pressure

Hypertension should be detected and treated as it is a major aetiological factor in atheroscleroses. This should form a routine part of any assessment in hospital or community. As mentioned the damaged heart may not be able to sustain a normal blood pressure. This means that regular blood pressure measuring can be a useful parameter for monitoring the evolution of an individual`s condition. Hypotension may also occur as a side effect of drugs such as beta blockers.

 

Respirations

Respiratory distress may indicate the onset of pulmonary oedema. Short gasping respiration often mean a pain is being caused by the respiratory effort. This may indicate muscular skeletal chest injury, lobal pneumonia or possible a pericarditis. Tachypnoea may indicate heart failure or pulmonary embolism. The general pallor of the individual should be monitored, with particular reference to signs of cyanosis.

 

Cardiac monitor

A cardiac monitor gives a continuous readout of the three lead electrocardiograph. This allows the early detection of any arrhythmias. A nurse may observe a cardiac arrest on the monitor and start taking appropriate action before the patient loses consciousness. Most systems allow for the printing out of significant rhythm strips. As it takes time and experience to learn the interpretation of the ECG monitor they are usually used in coronary care units

 

Patient reporting

Of course the patient will report essential assessment data. This will include duration, location radiation and severity of pain. Normally a "pain thermometer" will be used to achieve consistency. Shortness of breath, palpitations and anxiety may also be reported. It must be remembered that all cardiac patients will be anxious, it is only the degree of anxiety which will vary. Psychological depression is a danger which should be detected early as effective treatments are available. Threats to self-esteem and changes to body image are largely responsible for such affective changes.

 

 

Endocarditis

This is a condition affecting the lining of the heart and it may be caused by a variety of infecting organisms. For example streptococcus viridans or staphylococcus aureus. The infection of the lining of the heart affects the heart valves and this is a particular problem because fibrin and platelets, in combination with the infective organisms accumulate on the valves of the heart. This accumulation of abnormal material is termed vegetation. Emboli can break off from this vegetation causing small areas of infarct in organs such as the spleen, kidneys, myocardium or lungs.

 

Given that endocarditis is an infection, what clinical features might you expect to see?

 

Pyrexia

Malase

 

 

In addition to these features you have mentioned there may be heart murmurs.

 

Given that endocarditis is an infection causes by bacteria suggest some possible treatments for the condition.

 

Antibiotics

Rest

 

 

Given that endocarditis is an infection suggest some possible investigations which may be carried out.

 

Blood cultures to determine the aetiological organism

Echocardiography to check on valve function

 

 

Prophylaxis in endocardial abnormalities

Patients at risk of developing endocarditis should receive antibiotic prophylaxis before undergoing procedures likely to result in bacteraemia, such as dental extractions or even dental fillings. Patients at increased risk of developing valvular vegetation include those who have had rheumatic fever in the past. Such patients should be clearly identified so that appropriate prophylaxis may be offered prior to potential bacteremia causing procedures.

 

 

 

 

*           PQRST in the right order

*           PQRST phases are regular                         *           rate between 60 and 100

Table. 1 The three criteria for a normal sinus rhythm.

 

*           ischaemia

*           infarction                                                        *           aneurysm

Table 2. The three complications of atherosclerosis

 

*           sedentary life style

*           high fat diet                                                    *           lack of fruit and vegetables

*           smoking                                                         *           psychological stress            

*           male gender                                                  *           age                                        

*           hyperlipidaemia

*           obesity                                                            *           hypothyroid disease

*           poorly controlled diabetes mellitus              *           hypertension 

*           hereditary

Table 3. Factors in the aetiology of coronary arterial disease

 

*           arrthymias

*           heart block                                                     *           cardiac rupture

*           shock                                                              *           heart failure

Table 4. Possible complications of myocardial infarction

 

References.

1. Houston JC. Joiner CL. Trounce JR. (1987) A short textbook of medicine, Unibooks, Hodder and Stoughton, London.

2. Anderson KN. Anderson LE. Glanze WG. (1994) Mosby`s dictionary, Mosby, St Louis.

3. British heart foundation, (1986), Congenital heart disease, Heart information series no. 5

4. Green JH. (1974) An introduction to human physiology, Oxford medical publications, London

5. Guyton AC. (1991) Textbook of medical physiology, WB. Sanders Co. Philadelphia

6. British heart foundation, (1992), The heart, Heart information series no. 11

7. British heart foundation, (1992), Reducing the risk of a heart attack, Heart information series no. 14

8. Hulley SB.  Newman TB.  Grady D.  Garber AM.  Baron RB.  Browner WS. (1993) Should we be measuring blood cholesterol levels in young adults? JAMA.  269(11):1416-9, Mar 17.

9.  British heart foundation, (1989), Pacemakers, Heart information series no. 9

10. British heart foundation, (1989), Valvular heart disease, Heart information series no. 13

11. Kumar PJ. Clark LM. (1987), Clinical medicine, Bailliere Tindall.